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TREC
2003
15 years 1 months ago
Knowledge-Based Access to the Bio-Medical Literature, Ontologically-Grounded Experiments for the TREC 2003 Genomics Track
The Tarragon Consulting team participated in the primary task of the TREC 2003 Genomics Track. We used a combination of knowledge-engineering and corpus analysis to construct sema...
Richard Tong, John Quackenbush, Mark Snuffin
BMCBI
2010
118views more  BMCBI 2010»
14 years 11 months ago
Computing H/D-Exchange rates of single residues from data of proteolytic fragments
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
Ernst Althaus, Stefan Canzar, Carsten Ehrler, Mark...
BMCBI
2008
121views more  BMCBI 2008»
14 years 11 months ago
Modularization of biochemical networks based on classification of Petri net t-invariants
Background: Structural analysis of biochemical networks is a growing field in bioinformatics and systems biology. The availability of an increasing amount of biological data from ...
Eva Grafahrend-Belau, Falk Schreiber, Monika Heine...
BMCBI
2008
145views more  BMCBI 2008»
14 years 11 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2008
152views more  BMCBI 2008»
14 years 11 months ago
JCoast - A biologist-centric software tool for data mining and comparison of prokaryotic (meta)genomes
Background: Current sequencing technologies give access to sequence information for genomes and metagenomes at a tremendous speed. Subsequent data processing is mainly performed b...
Michael Richter, Thierry Lombardot, Ivaylo Kostadi...