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BMCBI
2011
14 years 6 months ago
Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
Stefan Wolfsheimer, Inke Herms, Sven Rahmann, Alex...
BMCBI
2011
14 years 6 months ago
RAIphy: Phylogenetic classification of metagenomics samples using iterative refinement of relative abundance index profiles
Background: Computational analysis of metagenomes requires the taxonomical assignment of the genome contigs assembled from DNA reads of environmental samples. Because of the diver...
Ozkan U. Nalbantoglu, Samuel F. Way, Steven H. Hin...
BMCBI
2011
14 years 6 months ago
Support vector machines-based identification of alternative splicing in Arabidopsis thaliana from whole-genome tiling arrays
Background: Alternative splicing (AS) is a process which generates several distinct mRNA isoforms from the same gene by splicing different portions out of the precursor transcript...
Johannes Eichner, Georg Zeller, Sascha Laubinger, ...
BMCBI
2011
14 years 6 months ago
Multiclass classification of microarray data samples with a reduced number of genes
Background: Multiclass classification of microarray data samples with a reduced number of genes is a rich and challenging problem in Bioinformatics research. The problem gets hard...
Elizabeth Tapia, Leonardo Ornella, Pilar Bulacio, ...
BMCBI
2011
14 years 6 months ago
Bio: : Phylo - phyloinformatic analysis using Perl
Background: Phyloinformatic analyses involve large amounts of data and metadata of complex structure. Collecting, processing, analyzing, visualizing and summarizing these data and...
Rutger A. Vos, Jason Caravas, Klaas Hartmann, Mark...
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