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BMCBI
2011
14 years 6 months ago
Clinical Synopsis Search in OMIM
Background: The OMIM database is a tool used daily by geneticists. Syndrome pages include a Clinical Synopsis section containing a list of known phenotypes comprising a clinical s...
Raphael Cohen, Avitan Gefen, Michael Elhadad, Ohad...
BMCBI
2011
14 years 6 months ago
The impact of quantitative optimization of hybridization conditions on gene expression analysis
Background: With the growing availability of entire genome sequences, an increasing number of scientists can exploit oligonucleotide microarrays for genome-scale expression studie...
Peter Sykacek, David P. Kreil, Lisa A. Meadows, Ri...
BMCBI
2011
14 years 6 months ago
The dChip survival analysis module for microarray data
Background: Genome-wide expression signatures are emerging as potential marker for overall survival and disease recurrence risk as evidenced by recent commercialization of gene ex...
Samir B. Amin, Parantu K. Shah, Aimin Yan, Sophia ...
BMCBI
2011
14 years 6 months ago
Meta-analysis of gene expression microarrays with missing replicates
Background: Many different microarray experiments are publicly available today. It is natural to ask whether different experiments for the same phenotypic conditions can be combin...
Fan Shi, Gad Abraham, Christopher Leckie, Izhak Ha...
BMCBI
2011
14 years 6 months ago
pROC: an open-source package for R and S+ to analyze and compare ROC curves
Background: Receiver operating characteristic (ROC) curves are useful tools to evaluate classifiers in biomedical and bioinformatics applications. However, conclusions are often r...
Xavier Robin, Natacha Turck, Alexandre Hainard, Na...
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