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BMCBI
2011
14 years 2 months ago
Robust joint analysis allowing for model uncertainty in two-stage genetic association studies
Background: The cost efficient two-stage design is often used in genome-wide association studies (GWASs) in searching for genetic loci underlying the susceptibility for complex di...
Dongdong Pan, Qizhai Li, Ningning Jiang, Aiyi Liu,...
BMCBI
2011
14 years 2 months ago
Detection of recurrent rearrangement breakpoints from copy number data
Background: Copy number variants (CNVs), including deletions, amplifications, and other rearrangements, are common in human and cancer genomes. Copy number data from array compara...
Anna M. Ritz, Pamela L. Paris, Michael Ittmann, Co...
BMCBI
2011
14 years 2 months ago
ShoRAH: estimating the genetic diversity of a mixed sample from next-generation sequencing data
Background: With next-generation sequencing technologies, experiments that were considered prohibitive only a few years ago are now possible. However, while these technologies hav...
Osvaldo Zagordi, Arnab Bhattacharya, Nicholas Erik...
BMCBI
2011
14 years 2 months ago
The Proteogenomic Mapping Tool
Background: High-throughput mass spectrometry (MS) proteomics data is increasingly being used to complement traditional structural genome annotation methods. To keep pace with the...
William S. Sanders, Nan Wang, Susan M. Bridges, Br...
BMCBI
2011
14 years 2 months ago
A user-friendly web portal for T-Coffee on supercomputers
Background: Parallel T-Coffee (PTC) was the first parallel implementation of the T-Coffee multiple sequence alignment tool. It is based on MPI and RMA mechanisms. Its purpose is t...
Josep Rius Torrento, Fernando Cores, Francesc Sols...
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