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IEAAIE
2000
Springer
15 years 1 months ago
Maintenance of KBS's by Domain Experts: The Holy Grail in Practice
Enabling a domain expert to maintain his own knowledge in a Knowledge Based System has long been an ideal for the Knowledge Engineering community. In this paper we report on our ex...
Arne Bultmann, Joris Kuipers, Frank van Harmelen
AAAI
1997
14 years 11 months ago
Building Concept Representations from Reusable Components
Our goal is to build knowledge-based systems capable of answering a wide variety of questions, including questions that are unanticipated when the knowledge base is built. For sys...
Peter Clark, Bruce W. Porter
BMCBI
2008
141views more  BMCBI 2008»
14 years 9 months ago
Ontology-guided data preparation for discovering genotype-phenotype relationships
Complexity of post-genomic data and multiplicity of mining strategies are two limits to Knowledge Discovery in Databases (KDD) in life sciences. Because they provide a semantic fr...
Adrien Coulet, Malika Smaïl-Tabbone, Pascale ...
BMCBI
2006
127views more  BMCBI 2006»
14 years 9 months ago
Construction of phylogenetic trees by kernel-based comparative analysis of metabolic networks
Background: To infer the tree of life requires knowledge of the common characteristics of each species descended from a common ancestor as the measuring criteria and a method to c...
Sok June Oh, Je-Gun Joung, Jeong Ho Chang, Byoung-...
BMCBI
2007
157views more  BMCBI 2007»
14 years 9 months ago
Constructing gene co-expression networks and predicting functions of unknown genes by random matrix theory
Background: Large-scale sequencing of entire genomes has ushered in a new age in biology. One of the next grand challenges is to dissect the cellular networks consisting of many i...
Feng Luo, Yunfeng Yang, Jianxin Zhong, Haichun Gao...