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BMCBI
2007
146views more  BMCBI 2007»
14 years 9 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
93
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TC
2010
14 years 7 months ago
Network-on-Chip Hardware Accelerators for Biological Sequence Alignment
—The most pervasive compute operation carried out in almost all bioinformatics applications is pairwise sequence homology detection (or sequence alignment). Due to exponentially ...
Souradip Sarkar, Gaurav Ramesh Kulkarni, Partha Pr...
BIBE
2009
IEEE
252views Bioinformatics» more  BIBE 2009»
15 years 4 months ago
Multi-Agents System to Model Cell Signalling by Using Fuzzy Cognitive Maps. Application to Computer Simulation of Multiple Myelo
—In order to simulate biological processes, we use multi-agents system. However, modelling cell behavior in systems biology is complex and may be based on intracellular biochemic...
Vincent Rodin, Gabriel Querrec, Pascal Ballet, Fra...
ISB
2002
140views more  ISB 2002»
14 years 9 months ago
Computer system "Gene Discovery" for promoter structure analysis
Data Mining and Knowledge Discovery techniques proved to be efficient tools for variety of complex tasks in biology including DNA research. This paper presents implementation of th...
Eugenii E. Vityaev, Yuri L. Orlov, Oleg V. Vishnev...
ISBRA
2010
Springer
15 years 4 months ago
Fast Computation of the Exact Hybridization Number of Two Phylogenetic Trees
Abstract. Hybridization is a reticulate evolutionary process. An established problem on hybridization is computing the minimum number of hybridization events, called the hybridizat...
Yufeng Wu, Jiayin Wang