Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
Brain surface conformal mapping research has been successful and this motivates our more general investigation of 3D volumetric brain harmonic mapping. By transforming the full 3D...
Yalin Wang, Xianfeng Gu, Tony F. Chan, Paul M. Tho...
Background: When proteins are subjected to proteolytic digestion and analyzed by mass spectrometry using a method such as 2D LC MS/MS, only a portion of the proteotypic peptides a...
William S. Sanders, Susan M. Bridges, Fiona M. McC...
: This article describes a method for solving the geometric closure problem for simplified models of nucleic acid structures by using the constant bond lengths approximation. The r...
Background: Intrinsic fluctuations due to the stochastic nature of biochemical reactions can have large effects on the response of biochemical networks. This is particularly true ...
David Adalsteinsson, David McMillen, Timothy C. El...