In computational biology there is an increasing need to combine micro and macro views of the system of interest. Therefore, explicit means to describe micro and macro level and th...
Adelinde M. Uhrmacher, Roland Ewald, Mathias John,...
Motivation: High-throughput methods for detecting molecular interactions have produced large sets of biological network data with much more yet to come. Analogous to sequence alig...
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...
Background: Present-day `-omics' technologies produce overwhelming amounts of data which include genome sequences, information on gene expression (transcripts and proteins) a...
Maria Luisa Chiusano, Nunzio D'Agostino, Alessandr...
The dynamics of biological processes are often modeled as systems of nonlinear ordinary differential equations (ODE). An important feature of nonlinear ODEs is that seemingly minor...