We propose a two-step biclustering approach to mine co-regulation patterns of a given reference gene to discover other genes that function in a common biological process. Currently...
The choice of a good annealing schedule is necessary for good performance of simulated annealing for combinatorial optimization problems. In this paper, we pose the simulated anne...
Background: The extended use of microarray technologies has enabled the generation and accumulation of gene expression datasets that contain expression levels of thousands of gene...
Pedro Carmona-Saez, Roberto D. Pascual-Marqui, Fra...
One approach to reduce the complexity of the task in the analysis of large scale genome-wide expression is to group the genes showing similar expression patterns into what are cal...
Clustering methods are a useful and common first step in gene expression studies, but the results may be hard to interpret. We bring in explicitly an indicator of which genes tie ...