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BIOINFORMATICS
2011
14 years 5 months ago
ProDy: Protein Dynamics Inferred from Theory and Experiments
Summary: We developed a Python package, ProDy, for structurebased analysis of protein dynamics. ProDy allows for quantitative characterization of structural variations in heteroge...
Ahmet Bakan, Lidio M. Meireles, Ivet Bahar
FLAIRS
2008
15 years 3 months ago
Contrast Pattern Mining with Gap Constraints for Peptide Folding Prediction
1 In this paper, we propose a peptide folding prediction method which discovers contrast patterns to differentiate and predict peptide folding classes. A contrast pattern is defin...
Chinar C. Shah, Xingquan Zhu, Taghi M. Khoshgoftaa...
BMCBI
2010
118views more  BMCBI 2010»
15 years 1 months ago
Computing H/D-Exchange rates of single residues from data of proteolytic fragments
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
Ernst Althaus, Stefan Canzar, Carsten Ehrler, Mark...
BMCBI
2010
116views more  BMCBI 2010»
15 years 1 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
CP
2003
Springer
15 years 6 months ago
Propagating N-Ary Rigid-Body Constraints
In this paper, we present an algorithm to propagate an n-ary constraint (with n greater than 2) specifying the relative positions of points in a three-dimensional rigid group. The ...
Ludwig Krippahl, Pedro Barahona