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ESANN
2006
15 years 1 months ago
Using sampling methods to improve binding site predictions
Currently the best algorithms for transcription factor binding site prediction are severely limited in accuracy. In previous work we combine random selection under-sampling with th...
Yi Sun, Mark Robinson, Rod Adams, Rene te Boekhors...
105
Voted
TOOLS
1999
IEEE
15 years 4 months ago
Towards Integration of State Machines and Object-Oriented Languages
The goal of this paper is to obtain a one-to-one correspondence between state machines as e.g. used in UML and object-oriented programming languages. A proposal is made for a lang...
Ole Lehrmann Madsen
112
Voted
RECOMB
2006
Springer
16 years 21 days ago
Improving Prediction of Zinc Binding Sites by Modeling the Linkage Between Residues Close in Sequence
Abstract. We describe and empirically evaluate machine learning methods for the prediction of zinc binding sites from protein sequences. We start by observing that a data set consi...
Sauro Menchetti, Andrea Passerini, Paolo Frasconi,...
BMCBI
2007
126views more  BMCBI 2007»
15 years 15 days ago
High-throughput identification of interacting protein-protein binding sites
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Jo-Lan Chung, Wei Wang, Philip E. Bourne
80
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ICMLA
2007
15 years 1 months ago
SVMotif: A Machine Learning Motif Algorithm
We describe SVMotif, a support vector machine-based learning algorithm for identification of cellular DNA transcription factor (TF) motifs extrapolated from known TF-gene interact...
Mark A. Kon, Yue Fan, Dustin T. Holloway, Charles ...