Histones are DNA-binding proteins found in the chromatin of all eukaryotic cells. They are highly conserved and can be grouped into five major classes: H1/H5, H2A, H2B, H3, and H4...
We present a new machine learning approach for 3D-QSAR, the task of predicting binding affinities of molecules to target proteins based on 3D structure. Our approach predicts bind...
Coupling is the action of binding two entities so that they can operate together to provide new functions. In this article, we propose a formal definition for coupling and present ...
While modern CPUs offer an increasing number of cores with shared caches, prevailing execution engines for business processes, workflows, or Web service compositions have not been ...
Background: An important step in annotation of sequenced genomes is the identification of transcription factor binding sites. More than a hundred different computational methods h...
Geir Kjetil Sandve, Osman Abul, Vegard Walseng, Fi...