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» Binding as sets of scopes
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BMCBI
2007
126views more  BMCBI 2007»
14 years 10 months ago
Multiple non-collinear TF-map alignments of promoter regions
Background: The analysis of the promoter sequence of genes with similar expression patterns is a basic tool to annotate common regulatory elements. Multiple sequence alignments ar...
Enrique Blanco, Roderic Guigó, Xavier Messe...
JIB
2006
106views more  JIB 2006»
14 years 10 months ago
A structural keystone for drug design
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...
Kristian Rother, Mathias Dunkel, Elke Michalsky, S...
ASE
2005
140views more  ASE 2005»
14 years 10 months ago
Automated Procedure Construction for Deductive Synthesis
Deductive program synthesis systems based on automated theorem proving offer the promise of software that is correct by construction. However, the difficulty encountered in constru...
Steve Roach, Jeffrey Van Baalen
BMCBI
2005
150views more  BMCBI 2005»
14 years 10 months ago
Discover protein sequence signatures from protein-protein interaction data
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
Jianwen Fang, Ryan J. Haasl, Yinghua Dong, Gerald ...
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BMCBI
2002
109views more  BMCBI 2002»
14 years 10 months ago
Kangaroo - A pattern-matching program for biological sequences
Background: Biologists are often interested in performing a simple database search to identify proteins or genes that contain a well-defined sequence pattern. Many databases do no...
Doron Betel, Christopher W. V. Hogue