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» Binding as sets of scopes
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106
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BMCBI
2005
133views more  BMCBI 2005»
15 years 5 days ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...
88
Voted
BMCBI
2008
114views more  BMCBI 2008»
15 years 11 days ago
Testing the Coulomb/Accessible Surface Area solvent model for protein stability, ligand binding, and protein design
Background: Protein structure prediction and computational protein design require efficient yet sufficiently accurate descriptions of aqueous solvent. We continue to evaluate the ...
Marcel Schmidt am Busch, Anne Lopes, Najette Amara...
85
Voted
ICFP
2005
ACM
16 years 6 days ago
A unified category-theoretic formulation of typed binding signatures
We generalise Fiore et al's account of variable binding for untyped cartesian contexts and Tanaka's account of variable binding for untyped linear contexts to give an ac...
Miki Tanaka, John Power
113
Voted
NAR
2006
156views more  NAR 2006»
15 years 6 days ago
VOMBAT: prediction of transcription factor binding sites using variable order Bayesian trees
Variable order Markov models and variable order Bayesian trees have been proposed for the recognition of transcription factor binding sites, and it could be demonstrated that they...
Jan Grau, Irad E. Ben-Gal, Stefan Posch, Ivo Gross...
96
Voted
NAR
2011
204views Computer Vision» more  NAR 2011»
14 years 3 months ago
CLIPZ: a database and analysis environment for experimentally determined binding sites of RNA-binding proteins
The stability, localization and translation rate of mRNAs are regulated by a multitude of RNAbinding proteins (RBPs) that find their targets directly or with the help of guide RNA...
Mohsen Khorshid, Christoph Rodak, Mihaela Zavolan