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BMCBI
2010
105views more  BMCBI 2010»
15 years 16 days ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
CODES
2006
IEEE
15 years 6 months ago
Thermal-aware high-level synthesis based on network flow method
Lowering down the chip temperature is becoming one of the important design considerations, since temperature adversely and seriously affects many of design qualities, such as reli...
Pilok Lim, Taewhan Kim
108
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BMCBI
2006
148views more  BMCBI 2006»
15 years 14 days ago
Predicting Class II MHC-Peptide binding: a kernel based approach using similarity scores
Background: Modelling the interaction between potentially antigenic peptides and Major Histocompatibility Complex (MHC) molecules is a key step in identifying potential T-cell epi...
Jesper Salomon, Darren R. Flower
ERSHOV
1999
Springer
15 years 4 months ago
Binding-Time Analysis in Partial Evaluation: One Size Does Not Fit All
Abstract. Existing partial evaluators usually fix the strategy for binding-time analysis. But a single strategy cannot fulfill all goals without leading to compromises regarding ...
Niels H. Christensen, Robert Glück, Sø...
DAC
1995
ACM
15 years 4 months ago
Register Allocation and Binding for Low Power
This paper describes a technique for calculating the switching activity of a set of registers shared by di erent data values. Based on the assumption that the joint pdf (probabili...
Jui-Ming Chang, Massoud Pedram