Sciweavers

659 search results - page 38 / 132
» Binding as sets of scopes
Sort
View
117
Voted
BMCBI
2007
105views more  BMCBI 2007»
15 years 15 days ago
Finding regulatory elements and regulatory motifs: a general probabilistic framework
Over the last two decades a large number of algorithms has been developed for regulatory motif finding. Here we show how many of these algorithms, especially those that model bind...
Erik van Nimwegen
128
Voted
BMCBI
2006
203views more  BMCBI 2006»
15 years 16 days ago
Genome-wide prediction of transcriptional regulatory elements of human promoters using gene expression and promoter analysis dat
Background: A complete understanding of the regulatory mechanisms of gene expression is the next important issue of genomics. Many bioinformaticians have developed methods and alg...
Seon-Young Kim, YongSung Kim
BMCBI
2010
153views more  BMCBI 2010»
15 years 18 days ago
Metamotifs - a generative model for building families of nucleotide position weight matrices
Background: Development of high-throughput methods for measuring DNA interactions of transcription factors together with computational advances in short motif inference algorithms...
Matias Piipari, Thomas A. Down, Tim J. P. Hubbard
BMCBI
2010
100views more  BMCBI 2010»
15 years 18 days ago
A robust method for estimating gene expression states using Affymetrix microarray probe level data
Background: Microarray technology is a high-throughput method for measuring the expression levels of thousand of genes simultaneously. The observed intensities combine a non-speci...
Megu Ohtaki, Keiko Otani, Keiko Hiyama, Naomi Kame...
101
Voted
BMCBI
2007
97views more  BMCBI 2007»
15 years 18 days ago
Relating destabilizing regions to known functional sites in proteins
Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...
Benoit H. Dessailly, Marc F. Lensink, Shoshana J. ...