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BMCBI
2006
102views more  BMCBI 2006»
15 years 16 days ago
Predicting population coverage of T-cell epitope-based diagnostics and vaccines
Background: T cells recognize a complex between a specific major histocompatibility complex (MHC) molecule and a particular pathogen-derived epitope. A given epitope will elicit a...
Huynh-Hoa Bui, John Sidney, Kenny Dinh, Scott Sout...
JCB
2008
159views more  JCB 2008»
15 years 14 days ago
BayesMD: Flexible Biological Modeling for Motif Discovery
We present BayesMD, a Bayesian Motif Discovery model with several new features. Three different types of biological a priori knowledge are built into the framework in a modular fa...
Man-Hung Eric Tang, Anders Krogh, Ole Winther
NAR
2007
115views more  NAR 2007»
15 years 1 hour ago
PReMod: a database of genome-wide mammalian cis-regulatory module predictions
We describe PReMod, a new database of genomewide cis-regulatory module (CRM) predictions for both the human and the mouse genomes. The prediction algorithm, described previously i...
Vincent Ferretti, Christian Poitras, Dominique Ber...
BMCBI
2008
130views more  BMCBI 2008»
15 years 18 days ago
Structural descriptor database: a new tool for sequence-based functional site prediction
Background: The Structural Descriptor Database (SDDB) is a web-based tool that predicts the function of proteins and functional site positions based on the structural properties o...
Juliana S. Bernardes, Jorge H. Fernandez, Ana Tere...
BMCBI
2008
172views more  BMCBI 2008»
15 years 18 days ago
Compo: composite motif discovery using discrete models
Background: Computational discovery of motifs in biomolecular sequences is an established field, with applications both in the discovery of functional sites in proteins and regula...
Geir Kjetil Sandve, Osman Abul, Finn Drablø...