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» Binding as sets of scopes
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ECOOP
2005
Springer
15 years 3 months ago
Separation of Concerns with Procedures, Annotations, Advice and Pointcuts
There are numerous mechanisms for separation of concerns at the source code level. Three mechanisms that are the focus of recent attention – metadata annotations, pointcuts and a...
Gregor Kiczales, Mira Mezini
BMCBI
2008
133views more  BMCBI 2008»
14 years 10 months ago
CORE_TF: a user-friendly interface to identify evolutionary conserved transcription factor binding sites in sets of co-regulated
Background: The identification of transcription factor binding sites is difficult since they are only a small number of nucleotides in size, resulting in large numbers of false po...
Matthew S. Hestand, Michiel van Galen, Michel P. V...
77
Voted
SCP
2010
78views more  SCP 2010»
14 years 8 months ago
Scoping strategies for distributed aspects
Dynamic deployment of aspects brings greater flexibility and reuse potential, but requires a proper means for scoping aspects. Scoping issues are particularly crucial in a distri...
Éric Tanter, Johan Fabry, Rémi Douen...
BMCBI
2007
92views more  BMCBI 2007»
14 years 10 months ago
Nanopore current transduction analysis of protein binding to non-terminal and terminal DNA regions: analysis of transcription fa
Background: Synthetic transcription factors (STFs) promise to offer a powerful new therapeutic against Cancer, AIDS, and genetic disease. Currently, 10% of drugs are of this type,...
Stephen Winters-Hilt, Amanda Davis, Iftekhar Amin,...
BMCBI
2004
207views more  BMCBI 2004»
14 years 10 months ago
Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrep-resen
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
Davide Corà, Ferdinando Di Cunto, Paolo Pro...