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» Bioinformatics Data Profiling Tools: A Prelude to Metabolic ...
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111
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BMCBI
2008
145views more  BMCBI 2008»
15 years 15 days ago
Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis
Background: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, ...
Shameek Biswas, John D. Storey, Joshua M. Akey
104
Voted
BMCBI
2004
153views more  BMCBI 2004»
15 years 8 days ago
Computational protein biomarker prediction: a case study for prostate cancer
Background: Recent technological advances in mass spectrometry pose challenges in computational mathematics and statistics to process the mass spectral data into predictive models...
Michael Wagner, Dayanand N. Naik, Alex Pothen, Sri...
BMCBI
2006
159views more  BMCBI 2006»
15 years 13 days ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...
106
Voted
BMCBI
2007
135views more  BMCBI 2007»
15 years 15 days ago
LIMPIC: a computational method for the separation of protein MALDI-TOF-MS signals from noise
Background: Mass spectrometry protein profiling is a promising tool for biomarker discovery in clinical proteomics. However, the development of a reliable approach for the separat...
Dante Mantini, Francesca Petrucci, Damiana Pierago...
IMSCCS
2006
IEEE
15 years 6 months ago
Clustering of Gene Expression Data: Performance and Similarity Analysis
Background: DNA Microarray technology is an innovative methodology in experimental molecular biology, which has produced huge amounts of valuable data in the profile of gene expre...
Longde Yin, Chun-Hsi Huang