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BIOINFORMATICS
2005
140views more  BIOINFORMATICS 2005»
15 years 3 months ago
Profile-based direct kernels for remote homology detection and fold recognition
Motivation: Remote homology detection between protein sequences is a central problem in computational biology. Supervised learning algorithms based on support vector machines are ...
Huzefa Rangwala, George Karypis
114
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BIOINFORMATICS
2005
85views more  BIOINFORMATICS 2005»
15 years 3 months ago
An automated genotyping system for analysis of HIV-1 and other microbial sequences
Motivation: Genetic analysis of HIV-1 is important not only for vaccine development, but also to guide treatment strategies, track the emergence of new viral variants and ensure t...
Tulio de Oliveira, Koen Deforche, Sharon Cassol, M...
118
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BIOINFORMATICS
2005
71views more  BIOINFORMATICS 2005»
15 years 3 months ago
Semi-supervised protein classification using cluster kernels
A key issue in supervised protein classification is the representation of input sequences of amino acids. Recent work using string kernels for protein data has achieved state-of-t...
Jason Weston, Christina S. Leslie, Eugene Ie, Deng...
156
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BMCBI
2005
125views more  BMCBI 2005»
15 years 3 months ago
Amino-Acid Substitutions In Membrane Proteins: Applications To Homology Recognition And Comparative Modelling
ent> <title><p>BioSysBio: Bioinformatics and Systems Biology Conference</p></title> <note>Meeting abstracts
Younes Mokrab, Kenji Mizuguchi
BIOINFORMATICS
2004
83views more  BIOINFORMATICS 2004»
15 years 3 months ago
Haplotypes histories as pathways of recombinations
Motivation: The diversity of a haplotype, represented as a string of polymorphic sites along a DNA sequence, increases exponentially with the number of sites if recombinations are...
Nadia El-Mabrouk, Damian Labuda