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2004
ACM
15 years 10 months ago
Practical applitudes: case studies of applications of the ZigZag hypermedia system
ZigZag is a paradigm of hypermedia that consists of a multidimensional system of principled interconnections. Its basic features and specifications are now well known, but despite...
Adam Moore, James Goulding, Tim J. Brailsford, Hel...
CSB
2004
IEEE
115views Bioinformatics» more  CSB 2004»
15 years 9 months ago
PoPS: A Computational Tool for Modeling and Predicting Protease Specificity
Proteases play a fundamental role in the control of intra- and extracellular processes by binding and cleaving specific amino acid sequences. Identifying these targets is extremel...
Sarah E. Boyd, Maria J. García de la Banda,...
BIOINFORMATICS
2010
94views more  BIOINFORMATICS 2010»
15 years 5 months ago
Globally, unrelated protein sequences appear random
Motivation: To test whether protein folding constraints and secondary structure sequence preferences significantly reduce the space of amino acid words in proteins, we compared th...
Daniel T. Lavelle, William R. Pearson
145
Voted
BIOINFORMATICS
2010
109views more  BIOINFORMATICS 2010»
15 years 5 months ago
Phylogenetic networks do not need to be complex: using fewer reticulations to represent conflicting clusters
Phylogenetic trees are widely used to display estimates of how groups of species evolved. Each phylogenetic tree can be seen as a collection of clusters, subgroups of the species ...
Leo van Iersel, Steven Kelk, Regula Rupp, Daniel H...
BIOINFORMATICS
2010
87views more  BIOINFORMATICS 2010»
15 years 5 months ago
Improving protein secondary structure prediction using a simple k-mer model
Motivation: Existing methods for protein sequence analysis are generally firstorder and inherently assume that each position is independent. We develop a general framework for int...
Martin Madera, Ryan Calmus, Grant Thiltgen, Kevin ...