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BIOTECHNO
2008
IEEE
15 years 12 months ago
Exploiting Codon-Triplets Association for Genome Primary Structure Analysis
— The way evolution shapes the arrangement of synonymous codons within open reading frames (ORF) for fine tuning mRNA decoding efficiency is not yet understood. Since the ribosom...
José P. Lousado, Gabriela R. Moura, Manuel ...
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BIOTECHNO
2008
IEEE
15 years 12 months ago
Grouping Levels of Exposure with Same Observable Effects before Class Prediction in Toxicogenomics
—Gene expression profiling in toxicogenomics is often used to find molecular signature of toxicants. The range of doses chosen in toxicogenomics studies does not always represe...
Vincent Guillemot, Cathy Philippe, Arthur Tenenhau...
BIOTECHNO
2008
IEEE
15 years 12 months ago
Mathematical Description of Biological Structures and Mechanisms
A new formalism and approach to describing cellular and molecular processes and structures is introduced, designed to support the creation of knowledge bases of molecular and cell...
H. Joel Jeffrey
BIBE
2007
IEEE
110views Bioinformatics» more  BIBE 2007»
15 years 11 months ago
Toward Petascale Simulation of Cellular Microphysiology
Abstract-MCell is a Monte Carlo simulator of cell microphysiology, and the scalable variant can be used to study challenging problems of interest to the biological community. MCell...
Scott B. Baden, Terrence J. Sejnowski, Thomas M. B...
BIBE
2007
IEEE
176views Bioinformatics» more  BIBE 2007»
15 years 11 months ago
HICCUP: Hierarchical Clustering Based Value Imputation using Heterogeneous Gene Expression Microarray Datasets
Abstract—A novel microarray value imputation method, HICCUP1 , is presented. HICCUP improves upon existing value imputation methods in the several ways. (1) By judiciously integr...
Qiankun Zhao, Prasenjit Mitra, Dongwon Lee, Jaewoo...