Federal agencies, academia and industries have invested heavily in the development of structural and biothermodynamic data. However, the data are still largely distributed over se...
Talapady N. Bhat, Yadu B. Tewari, Henry Rodriguez,...
Traditional phylogenetic tree reconstruction is based on point mutations of a single gene. This approach is hardly suitable for genomes whose genes are almost identical and hardly...
We have employed various sequence alignment algorithms and scoring techniques to determine whether current computational tools accurately predict genes that will be off-targeted b...
Amanda Birmingham, Emily M. Anderson, William S. M...
We have used quantitative modeling of signaling networks to show that the mitogen-activated protein kinase cascade — a highly-conserved signaling network in eukaryotes — can f...
Symbolic rewriting systems are gaining interest as tools for simulating biochemical dynamics. Compared to traditional methods based on differential equations, the symbolic approac...