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WABI
2010
Springer
143views Bioinformatics» more  WABI 2010»
15 years 3 months ago
Swiftly Computing Center Strings
The center string (or closest string) problem is a classical computer science problem with important applications in computational biology. Given k input strings and a distance thr...
Franziska Hufsky, Léon Kuchenbecker, Kathar...
WABI
2010
Springer
124views Bioinformatics» more  WABI 2010»
15 years 3 months ago
Improved Orientations of Physical Networks
Abstract. The orientation of physical networks is a prime task in deciphering the signaling-regulatory circuitry of the cell. One manifestation of this computational task is as a m...
Iftah Gamzu, Danny Segev, Roded Sharan
WABI
2010
Springer
177views Bioinformatics» more  WABI 2010»
15 years 3 months ago
Estimation of Alternative Splicing isoform Frequencies from RNA-Seq Data
In this paper we present a novel expectation-maximization algorithm for inference of alternative splicing isoform frequencies from high-throughput transcriptome sequencing (RNA-Seq...
Marius Nicolae, Serghei Mangul, Ion I. Mandoiu, Al...
WABI
2010
Springer
160views Bioinformatics» more  WABI 2010»
15 years 3 months ago
Genomic Distance with DCJ and Indels
The double cut and join (DCJ) operation, introduced by Yancopoulos, Attie and Friedberg in 2005, allows one to represent most rearrangement events in genomes. However, a DCJ cannot...
Marília D. V. Braga, Eyla Willing, Jens Sto...
WABI
2010
Springer
141views Bioinformatics» more  WABI 2010»
15 years 3 months ago
An Experimental Study of Quartets MaxCut and Other Supertree Methods
Although many supertree methods have been developed in the last few decades, none has been shown to produce more accurate trees than the popular Matrix Representation with Parsimon...
M. Shel Swenson, Rahul Suri, C. Randal Linder, Tan...