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CSB
2005
IEEE
136views Bioinformatics» more  CSB 2005»
15 years 9 months ago
An Algebraic Geometry Approach to Protein Structure Determination from NMR Data
Our paper describes the first provably-efficient algorithm for determining protein structures de novo, solely from experimental data. We show how the global nature of a certain ...
Lincong Wang, Ramgopal R. Mettu, Bruce Randall Don...
VRML
2004
ACM
15 years 9 months ago
PathSim visualizer: an Information-Rich Virtual Environment framework for systems biology
Increasingly, biology researchers and medical practitioners are using computational tools to model and analyze dynamic systems across scales from the macro to the cellular to the ...
Nicholas F. Polys, Doug A. Bowman, Chris North, Re...
CP
2003
Springer
15 years 9 months ago
A SAT-Based Approach to Multiple Sequence Alignment
Multiple sequence alignment is a central problem in Bioinformatics. A known integer programming approach is to apply branch-and-cut to exponentially large graph-theoretic models. T...
Steven David Prestwich, Desmond G. Higgins, Orla O...
BIBM
2009
IEEE
172views Bioinformatics» more  BIBM 2009»
15 years 9 months ago
Identifying Gene Signatures from Cancer Progression Data Using Ordinal Analysis
—A comprehensive understanding of cancer progression may shed light on genetic and molecular mechanisms of oncogenesis, and it may provide much needed information for effective d...
Yoon Soo Pyon, Jing Li
WABI
2001
Springer
110views Bioinformatics» more  WABI 2001»
15 years 8 months ago
Boosting EM for Radiation Hybrid and Genetic Mapping
Radiation hybrid (RH) mapping is a somatic cell technique that is used for ordering markers along a chromosome and estimating physical distances between them. It nicely complements...
Thomas Schiex, Patrick Chabrier, Martin Bouchez, D...