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DNA
2008
Springer
121views Bioinformatics» more  DNA 2008»
15 years 5 months ago
Isothermal Reactivating Whiplash PCR for Locally Programmable Molecular Computation
Whiplash PCR (WPCR), due to Hagiya et al. [1], is a novel technique for autonomous molecular computation where a state machine is implemented with a single stranded DNA molecule a...
John H. Reif, Urmi Majumder
131
Voted
BIBE
2010
IEEE
144views Bioinformatics» more  BIBE 2010»
15 years 4 months ago
Knowledge-Guided Docking of Flexible Ligands to SH2 Domain Proteins
Studies of interactions between protein domains and ligands are important in many aspects such as cellular signaling and regulation. In this work, we applied a three-stage knowledg...
Haiyun Lu, Shamima Banu Bte Sm Rashid, Hao Li, Wee...
132
Voted
BIBE
2010
IEEE
143views Bioinformatics» more  BIBE 2010»
15 years 4 months ago
The Effect of Sequence Error and Partial Training Data on BLAST Accuracy
- Metagenomics is the study of environmental samples. Because few tools exist for metagenomic analysis, a natural step has been to utilize the popular homology tool, BLAST, to sear...
Steven D. Essinger, Gail L. Rosen
142
Voted
BIBM
2007
IEEE
133views Bioinformatics» more  BIBM 2007»
15 years 3 months ago
Mining Clinical Data with a Temporal Dimension: A Case Study
Clinical databases store large amounts of information about patients and their medical conditions. Data mining techniques can extract relationships and patterns holding in this we...
Michele Berlingerio, Francesco Bonchi, Fosca Giann...
153
Voted
BIBM
2008
IEEE
125views Bioinformatics» more  BIBM 2008»
15 years 3 months ago
Systems Biology via Redescription and Ontologies (III): Protein Classification Using Malaria Parasite's Temporal Transcriptomic
This paper addresses the protein classification problem, and explores how its accuracy can be improved by using information from time-course gene expression data. The methods are ...
Antonina Mitrofanova, Samantha Kleinberg, Jane Car...