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164
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BMCBI
2008
122views more  BMCBI 2008»
15 years 3 months ago
Reconstructing networks of pathways via significance analysis of their intersections
Background: Significance analysis at single gene level may suffer from the limited number of samples and experimental noise that can severely limit the power of the chosen statist...
Mirko Francesconi, Daniel Remondini, Nicola Nerett...
122
Voted
BMCBI
2008
114views more  BMCBI 2008»
15 years 3 months ago
WSPMaker: a web tool for calculating selection pressure in proteins and domains using window-sliding
Background: In the study of adaptive evolution, it is important to detect the protein coding sites where natural selection is acting. In general, the ratio of the rate of non-syno...
Yong Seok Lee, Tae-Hyung Kim, Tae-Wook Kang, Won-H...
144
Voted
BMCBI
2008
135views more  BMCBI 2008»
15 years 3 months ago
Facilitating the development of controlled vocabularies for metabolomics technologies with text mining
Background: Many bioinformatics applications rely on controlled vocabularies or ontologies to consistently interpret and seamlessly integrate information scattered across public r...
Irena Spasic, Daniel Schober, Susanna-Assunta Sans...
125
Voted
BMCBI
2008
126views more  BMCBI 2008»
15 years 3 months ago
ISOL@: an Italian SOLAnaceae genomics resource
Background: Present-day `-omics' technologies produce overwhelming amounts of data which include genome sequences, information on gene expression (transcripts and proteins) a...
Maria Luisa Chiusano, Nunzio D'Agostino, Alessandr...
140
Voted
BMCBI
2008
103views more  BMCBI 2008»
15 years 3 months ago
Discovering multi-level structures in bio-molecular data through the Bernstein inequality
Background: The unsupervised discovery of structures (i.e. clusterings) underlying data is a central issue in several branches of bioinformatics. Methods based on the concept of s...
Alberto Bertoni, Giorgio Valentini