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WABI
2009
Springer
102views Bioinformatics» more  WABI 2009»
15 years 10 months ago
A Tree Based Method for the Rapid Screening of Chemical Fingerprints
Background: The fingerprint of a molecule is a bitstring based on its structure, constructed such that structurally similar molecules will have similar fingerprints. Molecular fin...
Thomas G. Kristensen, Jesper Nielsen, Christian N....
WABI
2009
Springer
129views Bioinformatics» more  WABI 2009»
15 years 10 months ago
biRNA: Fast RNA-RNA Binding Sites Prediction
We present biRNA, a novel algorithm for prediction of binding sites between two RNAs based on minimization of binding free energy. Similar to RNAup approach [30], we assume the bin...
Hamidreza Chitsaz, Rolf Backofen, Süleyman Ce...
171
Voted
WABI
2009
Springer
142views Bioinformatics» more  WABI 2009»
15 years 10 months ago
Back-Translation for Discovering Distant Protein Homologies
Background: Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from ...
Marta Gîrdea, Laurent Noé, Gregory Ku...
WABI
2009
Springer
155views Bioinformatics» more  WABI 2009»
15 years 10 months ago
A Markov Classification Model for Metabolic Pathways
Background: This paper considers the problem of identifying pathways through metabolic networks that relate to a specific biological response. Our proposed model, HME3M, first ide...
Timothy Hancock, Hiroshi Mamitsuka
125
Voted
WABI
2009
Springer
117views Bioinformatics» more  WABI 2009»
15 years 10 months ago
A Simulation Study Comparing Supertree and Combined Analysis Methods Using SMIDGen
Background: Supertree methods comprise one approach to reconstructing large molecular phylogenies given multi-marker datasets: trees are estimated on each marker and then combined...
M. Shel Swenson, François Barbançon,...