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BMCBI
2007
14 years 9 months ago
2007
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
BMCBI
2008
14 years 9 months ago
2008
Background: Protein structure analysis and comparison are major challenges in structural bioinformatics. Despite the existence of many tools and algorithms, very few of them have ...
BMCBI
2007
14 years 9 months ago
2007
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
BMCBI
2008
14 years 9 months ago
2008
Currently, most of the discovered biological and biomedical knowledge is available as textual data in scientific papers. And, locating and curating information about a genomic enti...
BMCBI
2008
14 years 9 months ago
2008
Background: The zebrafish is a powerful model vertebrate amenable to high throughput in vivo genetic analyses. Examples include reverse genetic screens using morpholino knockdown,...