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BMCBI
2006
85views more  BMCBI 2006»
14 years 9 months ago
Identification of physicochemical selective pressure on protein encoding nucleotide sequences
Background: Statistical methods for identifying positively selected sites in protein coding regions are one of the most commonly used tools in evolutionary bioinformatics. However...
Wendy S. W. Wong, Raazesh Sainudiin, Rasmus Nielse...
BMCBI
2006
120views more  BMCBI 2006»
14 years 9 months ago
Classification of protein quaternary structure by functional domain composition
Background: The number and the arrangement of subunits that form a protein are referred to as quaternary structure. Quaternary structure is an important protein attribute that is ...
Xiaojing Yu, Chuan Wang, Yixue Li
BMCBI
2006
112views more  BMCBI 2006»
14 years 9 months ago
Phylophenetic properties of metabolic pathway topologies as revealed by global analysis
Background: As phenotypic features derived from heritable characters, the topologies of metabolic pathways contain both phylogenetic and phenetic components. In the post-genomic e...
Yong Zhang, Shaojuan Li, Geir Skogerbø, Zhi...
BMCBI
2006
156views more  BMCBI 2006»
14 years 9 months ago
GOFFA: Gene Ontology For Functional Analysis - A FDA Gene Ontology Tool for Analysis of Genomic and Proteomic Data
Background: Gene Ontology (GO) characterizes and categorizes the functions of genes and their products according to biological processes, molecular functions and cellular componen...
Hongmei Sun, Hong Fang, Tao Chen, Roger Perkins, W...
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BMCBI
2006
121views more  BMCBI 2006»
14 years 9 months ago
Splice site identification using probabilistic parameters and SVM classification
Background: Recent advances and automation in DNA sequencing technology has created a vast amount of DNA sequence data. This increasing growth of sequence data demands better and ...
A. K. M. A. Baten, Bill C. H. Chang, Saman K. Halg...