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BMCBI
2006
134views more  BMCBI 2006»
14 years 9 months ago
A statistical score for assessing the quality of multiple sequence alignments
Background: Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein...
Virpi Ahola, Tero Aittokallio, Mauno Vihinen, Esa ...
BMCBI
2006
121views more  BMCBI 2006»
14 years 9 months ago
Robust computational reconstitution - a new method for the comparative analysis of gene expression in tissues and isolated cell
Background: Biological tissues consist of various cell types that differentially contribute to physiological and pathophysiological processes. Determining and analyzing cell type-...
Martin Hoffmann, Dirk Pohlers, Dirk Koczan, Hans-J...
BMCBI
2006
126views more  BMCBI 2006»
14 years 9 months ago
JUICE: a data management system that facilitates the analysis of large volumes of information in an EST project workflow
Background: Expressed sequence tag (EST) analyses provide a rapid and economical means to identify candidate genes that may be involved in a particular biological process. These E...
Mariano Latorre, Herman Silva, Juan Saba, Carito G...
BMCBI
2006
135views more  BMCBI 2006»
14 years 9 months ago
Correcting ligands, metabolites, and pathways
Background: A wide range of research areas in bioinformatics, molecular biology and medicinal chemistry require precise chemical structure information about molecules and reaction...
Martin A. Ott, Gert Vriend
BMCBI
2006
149views more  BMCBI 2006»
14 years 9 months ago
HeatMapper: powerful combined visualization of gene expression profile correlations, genotypes, phenotypes and sample characteri
Background: Accurate interpretation of data obtained by unsupervised analysis of large scale expression profiling studies is currently frequently performed by visually combining s...
Roel G. W. Verhaak, Mathijs A. Sanders, Maarten A....