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JCC
2007
82views more  JCC 2007»
14 years 9 months ago
Peptide reagent design based on physical and chemical properties of amino acid residues
: It has tremendous values for both drug discovery and basic research to develop a solid bioinformatical tool for guiding peptide reagent design. Based on the physical and chemical...
Qishi Du, Ri-Bo Huang, Yu-Tuo Wei, Cheng-Hua Wang,...
JIB
2007
95views more  JIB 2007»
14 years 9 months ago
Mining for Single Nucleotide Polymorphisms in Expressed Sequence Tags
As a multitude of sequence data are published, discovering polymorphisms bioinformatically becomes a valid option. In silico Single Nucleotide Polymorphism (SNP) detection is base...
E. L. Souche, B. Hellemans, J. K. J. Van Houdt, A....
80
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LOGCOM
2007
130views more  LOGCOM 2007»
14 years 9 months ago
A Logic for Concepts and Similarity
Categorisation of objects into classes is currently supported by (at least) two ‘orthogonal’ methods. In logic-based approaches, classifications are defined through ontologi...
Mikhail Sheremet, Dmitry Tishkovsky, Frank Wolter,...
84
Voted
BMCBI
2004
154views more  BMCBI 2004»
14 years 9 months ago
Base-By-Base: Single nucleotide-level analysis of whole viral genome alignments
Background: With ever increasing numbers of closely related virus genomes being sequenced, it has become desirable to be able to compare two genomes at a level more detailed than ...
Ryan Brodie, Alex J. Smith, Rachel L. Roper, Vasil...
BMCBI
2004
120views more  BMCBI 2004»
14 years 9 months ago
An approach to large scale identification of non-obvious structural similarities between proteins
Background: A new sequence independent bioinformatics approach allowing genome-wide search for proteins with similar three dimensional structures has been developed. By utilizing ...
Artem Cherkasov, Steven J. M. Jones