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BMCBI
2004
96views more  BMCBI 2004»
14 years 9 months ago
A hybrid clustering approach to recognition of protein families in 114 microbial genomes
Background: Grouping proteins into sequence-based clusters is a fundamental step in many bioinformatic analyses (e.g., homology-based prediction of structure or function). Standar...
Timothy J. Harlow, J. Peter Gogarten, Mark A. Raga...
BMCBI
2004
98views more  BMCBI 2004»
14 years 9 months ago
STING Millennium Suite: integrated software for extensive analyses of 3d structures of proteins and their complexes
Background: The integration of many aspects of protein/DNA structure analysis is an important requirement for software products in general area of structural bioinformatics. In fa...
Roberto H. Higa, Roberto C. Togawa, Arnaldo J. Mon...
BMCBI
2004
165views more  BMCBI 2004»
14 years 9 months ago
Analysis of oligonucleotide array experiments with repeated measures using mixed models
Background: Two or more factor mixed factorial experiments are becoming increasingly common in microarray data analysis. In this case study, the two factors are presence (Patients...
Hao Li, Constance L. Wood, Thomas V. Getchell, Mar...
BMCBI
2004
229views more  BMCBI 2004»
14 years 9 months ago
Automatic annotation of protein motif function with Gene Ontology terms
Background: Conserved protein sequence motifs are short stretches of amino acid sequence patterns that potentially encode the function of proteins. Several sequence pattern search...
Xinghua Lu, Chengxiang Zhai, Vanathi Gopalakrishna...
100
Voted
BMCBI
2004
95views more  BMCBI 2004»
14 years 9 months ago
PCOGR: Phylogenetic COG ranking as an online tool to judge the specificity of COGs with respect to freely definable groups of or
Background: The rapidly increasing number of completely sequenced genomes led to the establishment of the COG-database which, based on sequence homologies, assigns similar protein...
Florian Meereis, Michael Kaufmann