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BIOCOMP
2008
14 years 11 months ago
Reverse Engineering Module Networks by PSO-RNN Hybrid Modeling
Background: Inferring a gene regulatory network (GRN) from high throughput biological data is often an under-determined problem and is a challenging task due to the following reas...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
CBMS
2008
IEEE
15 years 3 months ago
ProtCV: A Tool for Extracting, Visualizing and Validating Protein Clusters Using Mass Spectra Peak-Lists
We present ProtCV (Protein Clustering and Visualization) a new software tool for grouping samples (mass spectra peak-lists) emanating from a high throughput proteomics analysis ba...
Stavroula Ventoura, Eugenia G. Giannopoulou, Elias...
BMCBI
2007
168views more  BMCBI 2007»
14 years 9 months ago
GOSim - an R-package for computation of information theoretic GO similarities between terms and gene products
Background: With the increased availability of high throughput data, such as DNA microarray data, researchers are capable of producing large amounts of biological data. During the...
Holger Fröhlich, Nora Speer, Annemarie Poustk...
BMCBI
2008
135views more  BMCBI 2008»
14 years 9 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
BMCBI
2006
138views more  BMCBI 2006»
14 years 9 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...