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BMCBI
2010
178views more  BMCBI 2010»
14 years 9 months ago
An improved method for scoring protein-protein interactions using semantic similarity within the Gene Ontology
Background: Semantic similarity measures are useful to assess the physiological relevance of protein-protein interactions (PPIs). They quantify similarity between proteins based o...
Shobhit Jain, Gary D. Bader
GECCO
2005
Springer
127views Optimization» more  GECCO 2005»
15 years 2 months ago
Identifying valid solutions for the inference of regulatory networks
In this paper, we address the problem of finding gene regulatory networks from experimental DNA microarray data. The problem often is multi-modal and therefore appropriate optimi...
Christian Spieth, Felix Streichert, Nora Speer, An...
AIIA
2009
Springer
15 years 4 months ago
Ontology-Driven Co-clustering of Gene Expression Data
Abstract. The huge volume of gene expression data produced by microarrays and other high-throughput techniques has encouraged the development of new computational techniques to eva...
Francesca Cordero, Ruggero G. Pensa, Alessia Visco...
BMCBI
2004
158views more  BMCBI 2004»
14 years 9 months ago
Incremental genetic K-means algorithm and its application in gene expression data analysis
Background: In recent years, clustering algorithms have been effectively applied in molecular biology for gene expression data analysis. With the help of clustering algorithms suc...
Yi Lu, Shiyong Lu, Farshad Fotouhi, Youping Deng, ...
BMCBI
2008
114views more  BMCBI 2008»
14 years 9 months ago
Partial mixture model for tight clustering of gene expression time-course
Background: Tight clustering arose recently from a desire to obtain tighter and potentially more informative clusters in gene expression studies. Scattered genes with relatively l...
Yinyin Yuan, Chang-Tsun Li, Roland Wilson