We consider the following problem: given a forest of gene family trees on a set of genomes, find a first speciation which splits these genomes into two subsets and minimizes the ...
Computational neuroscience is an appealing interdisciplinary domain, at the interface between biology and computer science. It aims at understanding the experimental data obtained...
Background: Many vital biological processes, including transcription and splicing, require a combination of short, degenerate sequence patterns, or motifs, adjacent to defined seq...
Micah Hamady, Erin Peden, Rob Knight, Ravinder Sin...
Diversity is an important source of robustness in biological systems. Computers, by contrast, are notable for their lack of diversity. Although homogeneous systems have many advan...
— Hannenhalli and Pevzner developed the first polynomial-time algorithm for the combinatorial problem of sorting of signed genomic data. Their algorithm solves the minimum numbe...