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BMCBI
2006
98views more  BMCBI 2006»
14 years 10 months ago
The Secrets of a Functional Synapse - From a Computational and Experimental Viewpoint
Background: Neuronal communication is tightly regulated in time and in space. The neuronal transmission takes place in the nerve terminal, at a specialized structure called the sy...
Michal Linial
97
Voted
RECOMB
2004
Springer
15 years 10 months ago
A class of edit kernels for SVMs to predict translation initiation sites in eukaryotic mRNAs
The prediction of translation initiation sites (TISs) in eukaryotic mRNAs has been a challenging problem in computational molecular biology. In this paper, we present a new algori...
Haifeng Li, Tao Jiang
RECOMB
1998
Springer
15 years 2 months ago
The hierarchical organization of molecular structure computations
The task of computing molecular structure from combinations of experimental and theoretical constraints is expensive because of the large number of estimated parameters (the 3D co...
Cheng Che Chen, Jaswinder Pal Singh, Russ B. Altma...
RECOMB
2004
Springer
15 years 10 months ago
Computational identification of evolutionarily conserved exons
Phylogenetic hidden Markov models (phylo-HMMs) have recently been proposed as a means for addressing a multispecies version of the ab initio gene prediction problem. These models ...
Adam C. Siepel, David Haussler
GECCO
1999
Springer
15 years 2 months ago
Reaction Temperature Constraints in DNA Computing
Using the thermodynamics of DNA melting, a technique is proposed to choose a reaction temperature for the DNA computation that minimizes the potential for mishybridizations. Adlem...
Russell J. Deaton