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97
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RECOMB
2002
Springer
15 years 10 months ago
Combining pairwise sequence similarity and support vector machines for remote protein homology detection
One key element in understanding the molecular machinery of the cell is to understand the meaning, or function, of each protein encoded in the genome. A very successful means of i...
Li Liao, William Stafford Noble
77
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IJON
2007
93views more  IJON 2007»
14 years 10 months ago
Computing with active dendrites
This paper introduces a new model of a spiking neuron with active dendrites and dynamic synapses (ADDS). The neuron employs the dynamics of the synapses and the active properties ...
Christo Panchev
ARC
2007
Springer
140views Hardware» more  ARC 2007»
15 years 2 months ago
Reconfigurable Computing for Accelerating Protein Folding Simulations
Abstract. This paper presents a methodology for the design of a reconfigurable computing system applied to a complex problem in molecular Biology: the protein folding problem. An e...
Nilton B. Armstrong, Heitor S. Lopes, Carlos R. Er...
RECOMB
2006
Springer
15 years 10 months ago
Alignment Statistics for Long-Range Correlated Genomic Sequences
It is well known that the base composition along eukaryotic genomes is long-range correlated. Here, we investigate the effect of such long-range correlations on alignment score sta...
Philipp W. Messer, Ralf Bundschuh, Martin Vingron,...
RECOMB
2006
Springer
15 years 10 months ago
Permutation Filtering: A Novel Concept for Significance Analysis of Large-Scale Genomic Data
Permutation of class labels is a common approach to build null distributions for significance analyis of microarray data. It is assumed to produce random score distributions, which...
Stefanie Scheid, Rainer Spang