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RECOMB
2004
Springer
16 years 3 months ago
Somatic evolution of cancer
We study a situation that arises in the somatic evolution of cancer. Consider a finite population of replicating cells and a sequence of mutations: type 0 can mutate to type 1, wh...
Martin Nowak
136
Voted
ASM
2008
ASM
15 years 5 months ago
The High Road to Formal Validation:
Abstract. In this paper we examine the difference between model checking high-level and low-level models. In particular, we compare the ProB model checker for the B-method and the ...
Michael Leuschel
ISMB
1998
15 years 4 months ago
Phylogenetic Inference in Protein Superfamilies: Analysis of SH2 Domains
This workfocuses on the inference of evolutionary relationships in protein superfamilies, and the uses of these relationships to identify keypositions in the structure, to infer a...
Kimmen Sjölander
RECOMB
2002
Springer
16 years 3 months ago
Significance Of inter-species matches when evolutionary rate varies
We develop techniques to estimate the statistical significance of gap-free alignments between two genomic DNA sequences, using human-mouse alignments as an example. The sequences ...
Jia Li, Webb Miller
ASM
2010
ASM
15 years 6 months ago
A Refinement-Based Correctness Proof of Symmetry Reduced Model Checking
Symmetry reduction is a model checking technique that can help alleviate the problem of state space explosion, by preventing redundant state space exploration. In previous work, we...
Edd Turner, Michael J. Butler, Michael Leuschel