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RECOMB
2009
Springer
16 years 3 months ago
Evaluating Between-Pathway Models with Expression Data
Abstract. Between-Pathway Models (BPMs) are network motifs consisting of pairs of putative redundant pathways. In this paper, we show how adding another source of high-throughput d...
Benjamin J. Hescott, Mark D. M. Leiserson, Lenore ...
RECOMB
2008
Springer
16 years 3 months ago
Ab Initio Whole Genome Shotgun Assembly with Mated Short Reads
Next Generation Sequencing (NGS) technologies are capable of reading millions of short DNA sequences both quickly and cheaply. While these technologies are already being used for r...
Paul Medvedev, Michael Brudno
RECOMB
2008
Springer
16 years 3 months ago
De Novo Sequencing of Nonribosomal Peptides
Abstract. While nonribosomal peptides (NRPs) are of tremendous pharmacological importance, there is currently no technology capable of highthroughput sequencing of NRPs. Difficulti...
Nuno Bandeira, Julio Ng, Dario Meluzzi, Roger G. L...
RECOMB
2006
Springer
16 years 3 months ago
Evolution of Tandemly Repeated Sequences Through Duplication and Inversion
Abstract. Given a phylogenetic tree T for a family of tandemly repeated genes and their signed order O on the chromosome, we aim to find the minimum number of inversions compatible...
Denis Bertrand, Mathieu Lajoie, Nadia El-Mabrouk, ...
RECOMB
2006
Springer
16 years 3 months ago
A Probabilistic Model for Gene Content Evolution with Duplication, Loss, and Horizontal Transfer
We introduce a Markov model for the evolution of a gene family along a phylogeny. The model includes parameters for the rates of horizontal gene transfer, gene duplication, and gen...
István Miklós, Miklós Csü...