Discrete motifsthat discriminate functionalclasses of proteins are useful for classifying newsequences, capturingstructural constraints, andidentifyingprotein subclasses.Despiteth...
Craig G. Nevill-Manning, Komal S. Sethi, Thomas D....
In bacterial cells, gene expression is regulated by multiple sigma factors, each of which has its promoter specificity, according to their conditions. Thus, if we can discriminate...
Sequencealignmentwithoutthe specification of gap penaltiesor a scoringmatrixis attainedbyusing Bayesianinferenceanda recursivealgorithm.Thisprocedure’srecursivealgorithmsumsover...
Virtually all large-scale sequencing projects use automatic sequence-assembly programs to aid in the determination of DNA sequences. The computer-generated assemblies require subs...
Carolyn F. Allex, Schuyler F. Baldwin, Jude W. Sha...
Thispaperintroducesa methodfor identifyingempirically conservedaminoacid substitution groups.In contrast with existing approachesthat viewaminoacid substitution as a pairwisepheno...