The next phase of human genomics will involve largescale screens of populations for signi cant DNA polymorphisms, notably single nucleotide polymorphisms SNP's. Dense human S...
Multiple sequence alignment (MSA) and phylogenetic tree reconstruction are one of the most important problems in the computational biology. While both these problems are of great ...
In this paper we define a class of formal neuron models being computationally efficient and biologically plausible, i.e., able to reproduce a wide range of behaviors observed in in...
Although analysis of genome rearrangements was pioneered by Dobzhansky and Sturtevant 65 years ago, we still know very little about the rearrangement events that produced the exis...
Algorithm development for comparing and aligning biological sequences has, until recently, been based on the SI model of mutational events which assumes that modi cation of sequen...