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15 years 5 months ago
A Practical Algorithm for Optimal Inference of Haplotypes from Diploid Populations
The next phase of human genomics will involve largescale screens of populations for signi cant DNA polymorphisms, notably single nucleotide polymorphisms SNP's. Dense human S...
Dan Gusfield
JPDC
2006
112views more  JPDC 2006»
15 years 3 months ago
Large scale multiple sequence alignment with simultaneous phylogeny inference
Multiple sequence alignment (MSA) and phylogenetic tree reconstruction are one of the most important problems in the computational biology. While both these problems are of great ...
Gilles Parmentier, Denis Trystram, Jaroslaw Zola
SIAMAM
2008
109views more  SIAMAM 2008»
15 years 3 months ago
Bifurcation Analysis of a General Class of Nonlinear Integrate-and-Fire Neurons
In this paper we define a class of formal neuron models being computationally efficient and biologically plausible, i.e., able to reproduce a wide range of behaviors observed in in...
Jonathan Touboul
RECOMB
2003
Springer
16 years 4 months ago
Transforming men into mice: the Nadeau-Taylor chromosomal breakage model revisited
Although analysis of genome rearrangements was pioneered by Dobzhansky and Sturtevant 65 years ago, we still know very little about the rearrangement events that produced the exis...
Pavel A. Pevzner, Glenn Tesler
RECOMB
1997
Springer
15 years 8 months ago
Sequence alignment with tandem duplication
Algorithm development for comparing and aligning biological sequences has, until recently, been based on the SI model of mutational events which assumes that modi cation of sequen...
Gary Benson