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DNA
2009
Springer
185views Bioinformatics» more  DNA 2009»
15 years 10 months ago
NP-Completeness of the Direct Energy Barrier Problem without Pseudoknots
Knowledge of energy barriers between pairs of secondary structures for a given DNA or RNA molecule is useful, both in understanding RNA function in biological settings and in desig...
Ján Manuch, Chris Thachuk, Ladislav Stacho,...
FCCM
2007
IEEE
117views VLSI» more  FCCM 2007»
15 years 10 months ago
FPGA Acceleration of Gene Rearrangement Analysis
In this paper we present our work toward FPGA acceleration of phylogenetic reconstruction, a type of analysis that is commonly performed in the fields of systematic biology and co...
Jason D. Bakos
RECOMB
2009
Springer
16 years 4 months ago
A Robust Bayesian Two-Sample Test for Detecting Intervals of Differential Gene Expression in Microarray Time Series
Abstract. Understanding the regulatory mechanisms that are responsible for an organism's response to environmental changes is an important question in molecular biology. A fir...
Oliver Stegle, Katherine J. Denby, David L. Wild, ...
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RECOMB
2007
Springer
16 years 4 months ago
GIMscan: A New Statistical Method for Analyzing Whole-Genome Array CGH Data
Genetic instability represents an important type of biological markers for cancer and many other diseases. Array Comparative Genome Hybridization (aCGH) is a high-throughput cytoge...
Yanxin Shi, Fan Guo, Wei Wu, Eric P. Xing
BICOB
2009
Springer
15 years 10 months ago
Generalized Binary Tanglegrams: Algorithms and Applications
Several applications require the joint display of two phylogenetic trees whose leaves are matched by inter-tree edges. This issue arises, for example, when comparing gene trees and...
Mukul S. Bansal, Wen-Chieh Chang 0002, Oliver Eule...