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BMCBI
2007
144views more  BMCBI 2007»
14 years 9 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...
BMCBI
2007
136views more  BMCBI 2007»
14 years 9 months ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette
BMCBI
2007
93views more  BMCBI 2007»
14 years 9 months ago
SVM-Fold: a tool for discriminative multi-class protein fold and superfamily recognition
Background: Predicting a protein’s structural class from its amino acid sequence is a fundamental problem in computational biology. Much recent work has focused on developing ne...
Iain Melvin, Eugene Ie, Rui Kuang, Jason Weston, W...
IANDC
2011
148views more  IANDC 2011»
14 years 4 months ago
Building species trees from larger parts of phylogenomic databases
Abstract. Gene trees are leaf-labeled trees inferred from molecular sequences. Due to duplication events arising in genome evolution, gene trees usually have multiple copies of som...
Celine Scornavacca, Vincent Berry, Vincent Ranwez
COLT
2008
Springer
14 years 11 months ago
Almost Tight Upper Bound for Finding Fourier Coefficients of Bounded Pseudo- Boolean Functions
A pseudo-Boolean function is a real-valued function defined on {0, 1}n . A k-bounded function is a pseudo-Boolean function that can be expressed as a sum of subfunctions each of w...
Sung-Soon Choi, Kyomin Jung, Jeong Han Kim