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BMCBI
2008
14 years 9 months ago
2008
Background: Expressed sequence tag (EST) collections are composed of a high number of single-pass, redundant, partial sequences, which need to be processed, clustered, and annotat...
BMCBI
2008
14 years 9 months ago
2008
Background: Solexa/Illumina short-read ultra-high throughput DNA sequencing technology produces millions of short tags (up to 36 bases) by parallel sequencing-by-synthesis of DNA ...
BMCBI
2007
14 years 9 months ago
2007
Background: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addre...
BMCBI
2008
14 years 9 months ago
2008
Background: Transcription factors (TFs) are core functional proteins which play important roles in gene expression control, and they are key factors for gene regulation network co...
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BMCBI
2007
14 years 9 months ago
2007
Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...