Synthetic biology is revolutionizing how we conceptualize and approach the engineering of biological systems. Recent advances in the field are allowing us to expand beyond the con...
Accurately estimating probabilities from observations is important for probabilistic-based approaches to problems in computational biology. In this paper we present a biologically...
Eleazar Eskin, William Stafford Noble, Yoram Singe...
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
Maria Rodriguez-Fernandez, Jose A. Egea, Julio R. ...
This is a time of increasing interdisciplinary research. Computer science is learning more from biology every day, enabling a plethora of new software techniques to flourish. And b...
We have developed a method to rapidly test the quality of a biological image, to identify appropriate segmentation methods that will render high quality segmentations for cells wit...