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» Biological Network Inference Using Redundancy Analysis
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BMCBI
2005
124views more  BMCBI 2005»
14 years 9 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
BMCBI
2007
135views more  BMCBI 2007»
14 years 9 months ago
Detecting multivariate differentially expressed genes
Background: Gene expression is governed by complex networks, and differences in expression patterns between distinct biological conditions may therefore be complex and multivariat...
Roland Nilsson, José M. Peña, Johan ...
BMCBI
2007
200views more  BMCBI 2007»
14 years 9 months ago
BNDB - The Biochemical Network Database
Background: Technological advances in high-throughput techniques and efficient data acquisition methods have resulted in a massive amount of life science data. The data is stored ...
Jan Küntzer, Christina Backes, Torsten Blum, ...
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CBMS
2001
IEEE
15 years 1 months ago
An Interoperable Data Architecture for Data Exchange in a Biomedical Research Network
Knowledge discovery and data correlation require a unified approach to basic data management. However, achieving such an approach is nearly impossible with hundreds of disparate d...
Daniel J. Crichton, J. Steven Hughes, Gregory J. D...
CIBCB
2007
IEEE
14 years 11 months ago
Optimization of Bacterial Strains with Variable-Sized Evolutionary Algorithms
—In metabolic engineering it is difficult to identify which set of genetic manipulations will result in a microbial strain that achieves a desired production goal, due to the co...
Miguel Rocha, José P. Pinto, Isabel Rocha, ...