Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...
Stochastic modeling forms the basis for analysis in many areas, including biological and economic systems, as well as the performance and reliability modeling of computers and comm...
— A key function for network traffic monitoring and analysis is the ability to perform aggregate queries over multiple data streams. Change detection is an important primitive w...
Robert T. Schweller, Zhichun Li, Yan Chen, Yan Gao...
The function of an unknown biological sequence can often be accurately inferred by identifying sequences homologous to the original sequence. Given a query set of known homologs, ...
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...