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» Biological Network Inference Using Redundancy Analysis
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WOB
2004
15 years 3 months ago
An Integrated Model for Cellular Analysis
ABSTRACT. We present the MOlecular NETwork (MONET) ontology as a model to integrate data from different networks that govern cell function. To achieve this, different existing onto...
Eduardo Battistella, José Souza, Clá...
111
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BMCBI
2007
114views more  BMCBI 2007»
15 years 2 months ago
Large scale statistical inference of signaling pathways from RNAi and microarray data
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
Holger Fröhlich, Mark Fellmann, Holger Sü...
128
Voted
BMCBI
2008
135views more  BMCBI 2008»
15 years 2 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
136
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EVOW
2007
Springer
15 years 8 months ago
Bio-mimetic Evolutionary Reverse Engineering of Genetic Regulatory Networks
The effective reverse engineering of biochemical networks is one of the great challenges of systems biology. The contribution of this paper is two-fold: 1) We introduce a new meth...
Daniel Marbach, Claudio Mattiussi, Dario Floreano
127
Voted
BMCBI
2010
138views more  BMCBI 2010»
15 years 2 months ago
A model-independent approach to infer hierarchical codon substitution dynamics
Background: Codon substitution constitutes a fundamental process in molecular biology that has been studied extensively. However, prior studies rely on various assumptions, e.g. r...
Olof Görnerup, Martin Nilsson Jacobi