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» Biological Networks: Comparison, Conservation, and Evolution...
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RECOMB
2006
Springer
15 years 10 months ago
Efficient Enumeration of Phylogenetically Informative Substrings
We study the problem of enumerating substrings that are common amongst genomes that share evolutionary descent. For example, one might want to enumerate all identical (therefore co...
Stanislav Angelov, Boulos Harb, Sampath Kannan, Sa...
ISMB
2003
14 years 11 months ago
Deriving phylogenetic trees from the similarity analysis of metabolic pathways
Comparative analysis of metabolic pathways in different genomes can give insights into the understanding of evolutionary and organizational relationships among species. This type ...
Maureen Heymans, Ambuj K. Singh
BMCBI
2010
176views more  BMCBI 2010»
14 years 9 months ago
TargetSpy: a supervised machine learning approach for microRNA target prediction
Background: Virtually all currently available microRNA target site prediction algorithms require the presence of a (conserved) seed match to the 5' end of the microRNA. Recen...
Martin Sturm, Michael Hackenberg, David Langenberg...
95
Voted
BMCBI
2004
150views more  BMCBI 2004»
14 years 9 months ago
Cross-species comparison significantly improves genome-wide prediction of cis-regulatory modules in Drosophila
Background: The discovery of cis-regulatory modules in metazoan genomes is crucial for understanding the connection between genes and organism diversity. It is important to quanti...
Saurabh Sinha, Mark D. Schroeder, Ulrich Unnerstal...
BMCBI
2006
117views more  BMCBI 2006»
14 years 9 months ago
SigFlux: A novel network feature to evaluate the importance of proteins in signal transduction networks
Background: Measuring each protein's importance in signaling networks helps to identify the crucial proteins in a cellular process, find the fragile portion of the biology sy...
Wei Liu, Dong Li, Jiyang Zhang, Yunping Zhu, Fuchu...